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Promethazine HCl Oral Remedy must be applied with warning in clients with bone-marrow despair. Leukopenia and agranulocytosis are claimed, ordinarily when Promethazine (Promethazine HCl) has actually been used in Affiliation with other acknowledged marrow-poisonous agents.Promethazine HCl Oral Remedy is contraindicated in comatose states, As well